What are the side effects of taking spironolactone?
Mia Phillips
Updated on June 09, 2026
- vomiting.
- diarrhea.
- stomach pain or cramps.
- enlarged or painful breasts in men or women.
- irregular menstrual periods.
.
Similarly one may ask, is Spironolactone safe for long term use?
BACKGROUND: Spironolactone has been used for over 20 years as an antiandrogen in the treatment of acne and hirsutism. No long-term studies of the safety of spironolactone used in this manner have been published. The long-term use of spironolactone in the treatment of acne in women appears to be safe.
One may also ask, what is the drug spironolactone used for? Spironolactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood). Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome.
Similarly, it is asked, what foods should be avoided when taking spironolactone?
Avoid taking salt substitutes that contain potassium or potassium supplements while taking spironolactone. Try to avoid foods high in potassium (such as avocados, bananas, coconut water, spinach, and sweet potato) because eating these foods may lead to potentially fatal hyperkalemia (high blood potassium levels).
Is weight gain a side effect of spironolactone?
There are concerns that spironolactone can cause weight gain, but there isn't much evidence it does. For example, the package insert for the drug doesn't list weight gain as a side effect. Along with weight gain, many people worry that spironolactone will make their skin look worse when they first start taking it.
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