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Velvet Digest

Can you withdraw from Effexor?

Author

Mia Phillips

Updated on May 04, 2026

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Also question is, how long does it take to withdraw from Effexor?

Effexor (Venlafaxine) Withdrawal Timeline And Symptom Durations. Although it is imperative to consult your doctor first, Effexor doses should be tapered off over seven to 10 days to avoid serious withdrawal symptoms. The medication should never be stopped cold turkey.

Furthermore, why is Effexor withdrawal so bad? However, during withdrawal of venlafaxine, both serotonin and noradrenaline levels decrease instead of increase, ruling out toxic levels of serotonin and noradrenaline as a probable cause of the withdrawal symptoms, that can be hypothesized to result from a (too) rapid deprivation of neurotransmitter levels.

One may also ask, what are the withdrawal symptoms of venlafaxine?

Venlafaxine withdrawal symptoms include:

  • Anxiety, confusion, or agitation.
  • Lack of coordination or vertigo.
  • Nausea, diarrhea, or vomiting.
  • Sleep disorders or nightmares.
  • Headache.
  • Dry mouth.
  • Fatigue.
  • Brain zaps (electric-like shocks)

Why has Effexor has been discontinued in the US?

Effexor is made by Wyeth Pharmaceuticals, Inc. and was approved by the U.S. Food and Drug Administration (FDA) in 1993. Effexor was discontinued because the newer time-released Effexor XR formula can be taken once daily and causes less nausea than the original formula.

Related Question Answers

Does Benadryl help with Effexor withdrawal?

If you were on a very high dose of Paxil (paroxetine) or Effexor (venlafaxine), you may need to take a second 20mg dose of Prozac. Benadryl (diphenhydramine) is an over-the-counter allergy medication that has been reported to help with discontinuation symptoms too, though it has a sedating effect.

What happens if you miss a day of Effexor?

What if I miss a dose of EFFEXOR XR? You should take EFFEXOR XR at about the same time every day. However, if you miss a dose, take the missed dose as soon as you remember. If you take too much EFFEXOR XR, call your doctor or poison control center or seek emergency treatment immediately.

What happens if I stop taking Effexor?

Do not stop taking venlafaxine, even when you feel better. Stopping venlafaxine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).

Can you take Effexor every other day?

One solution often proposed is to take one pill every other day, but some common antidepressants such as venlafaxine and paroxetine are broken down by the body within hours, so this method leads to drug levels in the blood fluctuating from one day to the next.

How do I quit effexor cold turkey?

You should not quit Effexor cold turkey. Doing so can result in withdrawal symptoms. Instead, it is recommended that you slowly taper off Effexor under a doctor's supervision.

Before Stopping Use

  1. Constipation: Exercise, such as going for a walk or jog, can help.
  2. Sleepiness: This side effect may last up to two weeks.

Can you stop taking Effexor immediately?

Do not stop taking venlafaxine, even when you feel better. Stopping venlafaxine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).

How does venlafaxine make you feel?

Venlafaxine can make you feel less hungry than usual, so you may lose weight when you start taking it. Some people might find they gain weight. If you start to have problems with your weight while taking venlafaxine, talk to your doctor or pharmacist.

Can Effexor cause long term damage?

Effexor (Venlafaxine) Long-Term Effects The FDA reports people taking antidepressants are 15 times more likely to commit suicide. Long-term use may also closely be associated with type 2 diabetes, according to the Journal of Clinical Psychiatry.

How do I come off venlafaxine?

Most patients tolerate a venlafaxine dosage reduction by 75 mg/d, at 1-week intervals. For patients who experience severe discontinuation symptoms with a minor dosage reduction, venlafaxine can be tapered over 10 months with approximately 1% dosage reduction every 3 days.

How long until venlafaxine is out of your system?

The overall average is around less than two days, though it depends on a variety of factors. Individual factors such as age, body composition, genetics and liver function play a critical role in how long it takes to flush venlafaxine out of your system.

Does venlafaxine give you energy?

Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI).

Can I lose weight on Effexor?

Effexor and Effexor XR may cause weight loss. This weight loss is usually small, but if a large weight loss occurs, it may be harmful to some patients. Talk to your doctor about this if you're concerned or if you start losing too much weight. Alcohol can increase the feeling of drowsiness this medication may cause.

Can you drink alcohol while taking venlafaxine?

Alcohol can increase the nervous system side effects of venlafaxine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with venlafaxine.

What happens if you forget to take your antidepressant?

Missed or extra doses It's important not to miss any of your doses, as this could make your treatment less effective. If you do miss 1 of your doses, take it as soon as you remember, unless it's almost time to take your next dose. In this case, you should just skip the missed dose.

How soon do withdrawal symptoms start?

The symptoms of opiate withdrawal come on in two stages. The onset of withdrawal symptoms, which usually begin within 24 hours after cessation, includes: Aching muscles. Feelings of restlessness and anxiety.

Is venlafaxine a good antidepressant?

Antidepressant Effexor Good Choice for Older Women. Effexor, an antidepressant that acts on two different brain chemicals, appears to be particularly helpful for middle-aged or older women, say researchers, who designed a study to compare the drug to the selective serotonin reuptake inhibitors.

Why does effexor cause weight loss?

This weight loss may be as a result of one of the more common side effects reported with Effexor: loss of appetite. Effexor's potential impact on the user's food drive could account for some of the weight loss reported by patients as they eat less food due to feeling hungry less often.

How long do brain zaps last after stopping Effexor?

Those who took antidepressants in higher doses for a longer time have more intense symptoms. Withdrawal symptoms typically persist for up to three weeks. The symptoms gradually fade during this time. Most people who quit taking their antidepressants stop having symptoms after three weeks.

What do brain zaps feel like?

Some sufferers describe them as "a sudden jolt or buzz in the brain." Others report that they feel like "short bursts of white light mixed with dizziness." Sometimes brain zaps are accompanied by vertigo, tinnitus, throat tension, and nausea. They are sometimes triggered by sudden movement of the eyes or the head.