Can you withdraw from Effexor?
Mia Phillips
Updated on May 04, 2026
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Also question is, how long does it take to withdraw from Effexor?
Effexor (Venlafaxine) Withdrawal Timeline And Symptom Durations. Although it is imperative to consult your doctor first, Effexor doses should be tapered off over seven to 10 days to avoid serious withdrawal symptoms. The medication should never be stopped cold turkey.
Furthermore, why is Effexor withdrawal so bad? However, during withdrawal of venlafaxine, both serotonin and noradrenaline levels decrease instead of increase, ruling out toxic levels of serotonin and noradrenaline as a probable cause of the withdrawal symptoms, that can be hypothesized to result from a (too) rapid deprivation of neurotransmitter levels.
One may also ask, what are the withdrawal symptoms of venlafaxine?
Venlafaxine withdrawal symptoms include:
- Anxiety, confusion, or agitation.
- Lack of coordination or vertigo.
- Nausea, diarrhea, or vomiting.
- Sleep disorders or nightmares.
- Headache.
- Dry mouth.
- Fatigue.
- Brain zaps (electric-like shocks)
Why has Effexor has been discontinued in the US?
Effexor is made by Wyeth Pharmaceuticals, Inc. and was approved by the U.S. Food and Drug Administration (FDA) in 1993. Effexor was discontinued because the newer time-released Effexor XR formula can be taken once daily and causes less nausea than the original formula.
Related Question AnswersDoes Benadryl help with Effexor withdrawal?
If you were on a very high dose of Paxil (paroxetine) or Effexor (venlafaxine), you may need to take a second 20mg dose of Prozac. Benadryl (diphenhydramine) is an over-the-counter allergy medication that has been reported to help with discontinuation symptoms too, though it has a sedating effect.What happens if you miss a day of Effexor?
What if I miss a dose of EFFEXOR XR? You should take EFFEXOR XR at about the same time every day. However, if you miss a dose, take the missed dose as soon as you remember. If you take too much EFFEXOR XR, call your doctor or poison control center or seek emergency treatment immediately.What happens if I stop taking Effexor?
Do not stop taking venlafaxine, even when you feel better. Stopping venlafaxine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).Can you take Effexor every other day?
One solution often proposed is to take one pill every other day, but some common antidepressants such as venlafaxine and paroxetine are broken down by the body within hours, so this method leads to drug levels in the blood fluctuating from one day to the next.How do I quit effexor cold turkey?
You should not quit Effexor cold turkey. Doing so can result in withdrawal symptoms. Instead, it is recommended that you slowly taper off Effexor under a doctor's supervision.Before Stopping Use
- Constipation: Exercise, such as going for a walk or jog, can help.
- Sleepiness: This side effect may last up to two weeks.