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Velvet Digest

Can spironolactone cause drowsiness?

Author

Eleanor Gray

Updated on June 27, 2026

Drowsiness and dizziness: Spironolactone may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Fluid and electrolyte balance: Spironolactone may cause the levels of electrolytes such as potassium, sodium, and chloride in the blood to change while taking this medication.

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Accordingly, does spironolactone make you tired?

YOU CAN FEEL MORE TIRED THAN USUAL "Spironolactone blocks the hormone aldosterone, which can lead to fatigue," Dr. Shah explains. "In addition, it can lower the blood pressure, and if this drop is sudden, you may feel tired."

Secondly, how fast does spironolactone leave your system? Spironolactone is metabolized into active sulfur-containing substances, and peak concentrations are reached within three to five hours. The effects of one dose of spironolactone usually last for 24 hours.

what are the side effects of spironolactone?

Common Side Effects of Spironolactone

  • Vomiting, diarrhea, and stomach pain or cramps.
  • Dry mouth and thirst.
  • Dizziness, unsteadiness, and headache.
  • Gynecomastia (enlarged breast tissue) in men, and breast pain in women.
  • Irregular menstrual periods and post-menopausal vaginal bleeding.
  • Erectile dysfunction.

Should I drink more water when taking spironolactone?

These conditions may cause you to lose too much water or salt and may lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. This medicine may cause swelling of the breasts (gynecomastia) and breast pain in some patients.

Related Question Answers

Does spironolactone affect mood?

Of the individual symptoms, spironolactone significantly improved irritability, depression, feeling of swelling, breast tenderness and food craving in comparison to placebo. CONCLUSIONS: Spironolactone appears to be an effective therapy for the negative mood changes and somatic symptoms in PMS.

How long does it take spironolactone to work for facial hair?

Spironolactone is very effective in lessening hair growth and improving acne for young women, especially those taking oral contraceptive pills. Most young women taking this medication will see positive results; however, it can take up to 6 months to see an improvement in symptoms.

Can spironolactone make you gain weight?

There are concerns that spironolactone can cause weight gain, but there isn't much evidence it does. For example, the package insert for the drug doesn't list weight gain as a side effect. Along with weight gain, many people worry that spironolactone will make their skin look worse when they first start taking it.

Does spironolactone make hair thicker?

Spironolactone slows down the production of androgens. These are male sex hormones, including testosterone. Reduced production of androgens can slow down the progression of hair loss caused by androgenic alopecia. This combination was associated with reduced shedding, increased hair growth, and thicker hair.

What time of day should you take spironolactone?

How to use Spironolactone. Take this medication by mouth, as directed by your doctor. If stomach upset occurs, take it with food or milk. It is best to take your dose early in the day (before 6 p.m.) to prevent having to get up during the night to urinate.

Will I lose muscle on spironolactone?

For example, spironolactone seems to be more effective than ACE inhibitors in keeping magnesium and potassium levels in muscles high – a highly desired effect for improving muscle strength. Spironolactone may thus be a promising medication to counter the decline in muscle function in elderly.

Can I stop spironolactone cold turkey?

While taking this drug, you should watch your potassium intake. You shouldn't take potassium supplements, eat a diet rich in potassium, or consume salt substitutes containing potassium. If this happens, your doctor may stop your treatment with this drug. This symptom usually goes away once you stop taking this drug.

Can I take spironolactone before bed?

Spironolactone is commonly prescribed just once daily and you can generally take the dose at a time to suit you. However, diuretics are best taken no later than mid-afternoon. However, if it is after 6 pm in the evening, skip the missed dose and continue as usual the next day.

Can spironolactone cause body aches?

Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction, hyperkalemia (high levels of potassium in the blood), and numbness.

Does spironolactone dry out your skin?

Spironolactone is in general very safe,” Dr. Herrmann tells TZR. “It doesn't risk resistance and gut disruption like many oral antibiotics or leave the skin overly dry and irritated like many topicals.” “It is prescribed at a very low dose for acne, so it does not affect your blood pressure,” Dr.

Is Spironolactone safe for long term use?

BACKGROUND: Spironolactone has been used for over 20 years as an antiandrogen in the treatment of acne and hirsutism. No long-term studies of the safety of spironolactone used in this manner have been published. The long-term use of spironolactone in the treatment of acne in women appears to be safe.

Can spironolactone cause eye problems?

This medicine may cause blurred vision or eye problems that could lead to vision loss. Contact your healthcare provider right away if you have eye pain or a decrease in vision. This medicine may increase your risk of dehydration. This medicine may make you dizzy or drowsy.

What is spironolactone 100mg used for?

Spironolactone is used to treat heart failure, high blood pressure (hypertension), or hypokalemia (low potassium levels in the blood). Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome.

Can spironolactone cause yeast infections?

Men can't take the medication because it blocks the effects of male hormones like testosterone. The side effects associated with oral antibiotics include stomach pain, yeast infections, and sun sensitivity in the short term and things like inflammatory bowel disease in the long term.

Can I take ibuprofen with spironolactone?

ibuprofen spironolactone Before taking spironolactone, tell your doctor if you also use ibuprofen. You may need dose adjustments or special tests in order to safely take both medications together. Do not stop using your medications without first talking to your doctor first.

Does spironolactone cause breast growth?

Spironolactone frequently causes breast pain and breast enlargement in women. Spironolactone also commonly and dose-dependently produces gynecomastia (breast development) as a side effect in men. At low doses, the rate is only 5 to 10%, but at high doses, up to or exceeding 50% of men may develop gynecomastia.

What should I monitor with spironolactone?

The recommended monitoring for potassium and creatinine is one week after initiation or increase in dose of ALDACTONE, monthly for the first 3 months, then quarterly for a year, and then every 6 months. Discontinue or interrupt treatment for serum potassium > 5 mEq/L or for serum creatinine > 4 mg/dL.

Can spironolactone help me lose weight?

Spironolactone is a prescription medication. There is no evidence that spironolactone works specifically for weight loss. But spironolactone might help reduce weight that's related to fluid retention, especially in women with bloating and swelling due to PMS.

How long should I take spironolactone for acne?

"If the oil glands do not make as much oil, there will be fewer blockages in the pores, less food to feed acne-causing bacteria, and less shininess," he says. Spironolactone results typically appear within a few weeks, but Zeichner says the drug reaches "peak effect" at around three months.