Can spironolactone cause drowsiness?
Eleanor Gray
Updated on June 27, 2026
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Accordingly, does spironolactone make you tired?
YOU CAN FEEL MORE TIRED THAN USUAL "Spironolactone blocks the hormone aldosterone, which can lead to fatigue," Dr. Shah explains. "In addition, it can lower the blood pressure, and if this drop is sudden, you may feel tired."
Secondly, how fast does spironolactone leave your system? Spironolactone is metabolized into active sulfur-containing substances, and peak concentrations are reached within three to five hours. The effects of one dose of spironolactone usually last for 24 hours.
what are the side effects of spironolactone?
Common Side Effects of Spironolactone
- Vomiting, diarrhea, and stomach pain or cramps.
- Dry mouth and thirst.
- Dizziness, unsteadiness, and headache.
- Gynecomastia (enlarged breast tissue) in men, and breast pain in women.
- Irregular menstrual periods and post-menopausal vaginal bleeding.
- Erectile dysfunction.
Should I drink more water when taking spironolactone?
These conditions may cause you to lose too much water or salt and may lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. This medicine may cause swelling of the breasts (gynecomastia) and breast pain in some patients.
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